Ken Bradley, Ph.D.
Anthrax is the disease resulting from infection by spores of the Gram-positive bacterium Bacillus anthracis. Virulence of B. anthracis is associated with two secreted protein toxins, edema toxin and lethal toxin, which are collectively referred to as anthrax toxin. Both of these two toxins ...(more)
Robert Gunsalus, Ph.D.
Regulation of Cellular Respiratory Functions in Microorganisms
Research interests of the Gunsalus laboratory address the physiology and molecular biology of gene expression in the Bacteria and Archaea. We are studying how cells sense changing environmental conditions, and adapt their metabolism accordingly. Experimental approaches ...(more)
Marcus Horwitz, M.D.
Dr. Horwitz is Professor of Medicine and Microbiology, Immunology, & Molecular Genetics. He received his M.D. degree from Columbia U. College of Physicians and Surgeons and subsequently trained in Internal Medicine and Infectious Diseases at the Albert Einstein ...(more)
Beth Lazazzera, Ph.D.
Mechanisms of Multicellular Behavior in Bacteria
Cell-cell signaling is a fundamental process carried out by all cell types. Bacteria communicate with each other to coordinate such processes development, antibiotic production, and virulence. We are studying the mechanism of cell-cell signaling in the model gram-positive bacterium ...(more)
Megan McEvoy, Ph.D.
The McEvoy laboratory is focused on developing an understanding of how organisms handle metal ions. Organisms can face highly varying levels of metal ions through their environment or diet, and metal ion concentrations in cells must be carefully regulated. Some metal cations, such as copper, cobalt, and nickel, are essential in trace amounts, though toxic at higher concentrations. ...(more)
James N. Miller, Ph.D.
Molecular and cellular approaches to the immunobiology and immuno pathogenesis of syphilis and Lyme borreliosis: (a) development of an early disease rabbit model for Lyme borreliosis, (b) vaccine development utilizing recombinant molecules, (c) operative humoral and cell ...(more)
Jeff F. Miller, Ph.D.
Sensory Transduction in the Control of Bacterial Virulence
We are investigating the role of sensory transduction in bacterial-host interactions. Genes and operons that encode virulence factors are often subject to coordinate regulation in response to environmental signals. In addition, bacterial virulence factors often target specific host cell ...(more)
Jeffrey H. Miller, Ph.D.
DNA Repair and Mutagenesis
Our laboratory studies mechanisms of DNA repair and mutagenesis, and mutation avoidance pathways. We use microorganisms to discover repair and mutation avoidance pathways, and then attempt to find counterparts in higher cells, including humans. The long term goals ...(more)
Erin R. Sanders, Ph.D.
Undergraduate — Lecturer & Academic Coordinator for MIMG Instructional Laboratories
Graduate — Co-Faculty Advisor for MIMG Teaching Assistants, Departmental TA Training Course (MIMG 495 – Preparation for Teaching Microbiology in Higher Education) & Programs ...(more)
Imke Schroeder, Ph.D.
Purification of Nitrate Reductase from a Hyperthermophylic Archaeon Pyrobaculum
The wide spread pollution of ground water with nitrate is an environmental problem and a health hazard. Nitrate/nitrite pollution is specially significant in agricultural regions where nitrate is used as fertilizer and where animal waste seeps into the water supply. The detection and ...(more)
Wenyuan Shi, Ph.D.
Biology and Biotechnology of Bacterial Pathogenesis
The scientific focus of my laboratory is to understand molecular mechanism of bacterial pathogenesis and to apply the knowledge to develop new biotechnology. There are five research projects in the laboratory which enable us to study oral bacterial pathogenesis ...(more)
Robert Simons, Ph.D.
Regulation of gene expression at the postranscriptional level Our laboratory is interested primarily in the regulation of gene expression at the postranscriptional level in simple cells like bacteria and yeast. This work focuses on RNA structure, RNA/protein interaction and ...(more)